Abstract

Short Communication

Advances in Physiological Research: Consideration on Arterial Hypercapnia in Acute Cardiogenic Pulmonary Edema (ACPE)

Andrea Bellone*

Published: 24 October, 2024 | Volume 8 - Issue 3 | Pages: 116-117

The causes of hypercapnia in Acute Cardiogenic Pulmonary Edema are still unknown. Our hypothesis recognizes an alteration of the ventilation-perfusion ratio in the apical areas of the lung as the major cause. The redistribution of blood to the apical lung zone in hypertensive pulmonary circulation determines an excess of perfusion compared to ventilation and consequently hypercapnia. Our suggestion might be in favor of Bilevel-PAP over Continuous Positive Airway Pressure (CPAP) as the first line of therapy.

Read Full Article HTML DOI: 10.29328/journal.acr.1001108 Cite this Article Read Full Article PDF

Keywords:

Acute cardiogenic pulmonary edema; Hypercapnia; Ventilation-perfusion ratio

References

  1. Nava S, Carbone G, DiBattista N, Bellone A, Baiardi P, Cosentini R, et al. Noninvasive ventilation in cardiogenic pulmonary edema: a multicenter randomized trial. Am J Respir Crit Care Med. 2003;168:1432-1437. Available from: https://doi.org/10.1164/rccm.200211-1270oc
  2. Bellone A, Monari A, Cortellaro F, Vettorello M, Arlati S, Coen D. Myocardial infarction rate in acute pulmonary edema: noninvasive pressure support ventilation versus continuous positive airway pressure. Crit Care Med. 2004;32:1860-1865. Available from: https://doi.org/10.1097/01.ccm.0000139694.47326.b6
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  9. Bellone A, Vettorello M, Monari A, Cortellaro F, Coen D. Noninvasive pressure support ventilation continuous positive airway pressure in acute hypercapnic pulmonary edema. Intensive Care Med. 2005;31:807-811. Available from: https://doi.org/10.1007/s00134-005-2649-6
  10. West JB. Regional differences in the lung. London and New York: Academic Press; 1976.

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