Abstract

Case Series

Other Applications of Amniotic Membranes: Case Series

Linda Guerrero*

Published: 23 December, 2024 | Volume 8 - Issue 3 | Pages: 159-162

The amniotic membrane, used for over a century, is a widely recognized therapeutic tool in regenerative medicine and reconstructive surgery. Its primary indication is in the treatment of deep partial-thickness burns, where it facilitates epithelialization by providing an optimal environment for tissue regeneration. However, its versatility allows its use in various clinical scenarios, particularly in wounds or trauma where immediate closure is not possible, either due to the patient’s condition or the characteristics of the wound itself. Its most notable benefits include the prevention of necrosis due to desiccation, minimizing the loss of essential proteins, fluids, and electrolytes, reducing the risk of infection by acting as a physical barrier and alleviating pain by covering and stabilizing the wound.
Additionally, its ability to act as a temporary biological cover offers a valuable solution in complex cases, improving both the prognosis and the patient’s management.
A case series is presented demonstrating various applications of the amniotic membrane.

Read Full Article HTML DOI: 10.29328/journal.acr.1001117 Cite this Article Read Full Article PDF

Keywords:

Amnion; Chorion; Temporary cover; Tissue bank

References

  1. Trelford JD, Trelford-Sauder M. The amnion in surgery, past and present. Am J Obstet Gynecol. 1979;134(7):833-845. Available from: https://doi.org/10.1016/0002-9378(79)90957-8
  2. Robson MC, Krizek TJ. The effect of human amniotic membranes on the bacterial population of infected rat burns. Ann Surg. 1973;177:144-149. Available from: https://doi.org/10.1097/00000658-197302000-00003
  3. Robson MC, Krizek TJ. Amniotic membranes as a temporary wound dressing. Surg Gynecol Obstet. 1973;136:904-906. Available from: https://pubmed.ncbi.nlm.nih.gov/4703471/
  4. Fairbairn NG, Randolph MA, Redmond RW. The clinical applications of human amnion in plastic surgery. J Plast Reconstr Aesthet Surg. 2014;67(5):662-675. Available from: https://doi.org/10.1016/j.bjps.2014.01.031
  5. Branski LK, Herndon DN, Celis MM, Norbury WB, Masters OE, Jeschke MG. Amnion in the treatment of pediatric partial-thickness facial burns. Burns. 2008;34(3):393-399. Available from: https://doi.org/10.1016/j.burns.2007.06.007
  6. Vloemans van der Wal H, Liebregts J, Middelkoop E. Optimal treatment of partial thickness burns in children: A systematic review. Burns. 2014;40(2):177-190. Available from: https://doi.org/10.1016/j.burns.2013.09.016

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