Mycobacterium colombiense in a Mexican Patient with HIV Identified by DNA Sequencing
Mycobacterium Colombiense
Article Sidebar
Main Article Content
Abstract
Mycobacterium colombiense is a rare nontuberculous mycobacterium (NTM) associated with respiratory disease, belonging to the Mycobacterium avium complex (MAC). We present the case of a 39-year-old male from Mexico City, diagnosed with stage 4 Human Immunodeficiency Virus (HIV), in whom Mycobacterium colombiense was isolated from bone marrow using DNA sequencing, without evidence of pulmonary disease. This is the first case of isolation in Mexico. Because NTM cultures take 2 – 3 weeks to grow, the diagnosis is generally delayed, highlighting the need to implement molecular testing for rapid diagnosis and timely treatment initiation .
Article Details
Copyright (c) 2025 Vázquez-Moreno J.
This work is licensed under a Creative Commons Attribution 4.0 International License.
The Archives of Case Reports is committed in making it easier for people to share and build upon the work of others while maintaining consistency with the rules of copyright. In order to use the Open Access paradigm to the maximum extent in true terms as free of charge online access along with usage right, we grant usage rights through the use of specific Creative Commons license.
License: Copyright © 2017 - 2025 | 
Open Access by Archives of Case Reports is licensed under a Creative Commons Attribution 4.0 International License. Based on a work at Heighten Science Publications Inc.
With this license, the authors are allowed that after publishing with the journal, they can share their research by posting a free draft copy of their article to any repository or website.
Compliance 'CC BY' license helps in:
| Permission to read and download | ✓ |
| Permission to display in a repository | ✓ |
| Permission to translate | ✓ |
| Commercial uses of manuscript | ✓ |
'CC' stands for Creative Commons license. 'BY' symbolizes that users have provided attribution to the creator that the published manuscripts can be used or shared. This license allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author.
Please take in notification that Creative Commons user licenses are non-revocable. We recommend authors to check if their funding body requires a specific license.
Leora Velasquez.Perez, a:1:{s:5:"en_US";s:50:"Instituto Nacional de Neurología y Neurocirugía ";}
Epidemiology department head. National Institute of Neurology and Neurosurgery[1] Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV. Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV. National Institutes of Health, HIV Medicine Association, and Infectious Diseases Society of America. Available at: https://clinicalinfo.hiv.gov/en/guidelines/adult-and-adolescent-opportunistic-infection
[2] Yu X, et al. Mycobacterium colombiense and Mycobacterium avium Complex Causing Severe Pneumonia in a Patient with HIV Identified by a Novel Molecular-Based Method. Infection and Drug Resistance. 2021; Vol 14, 11–6 [citado 03 Ene 2025]. DOI:10.2147/IDR.S282190. Disponible en: https://pmc.ncbi.nlm.nih.gov/articles/PMC7797356/
[3] Tang M, Zeng W, Qiu Y, Fang G, Pan M, Li W, et al. Clinical features of rare disseminated Mycobacterium colombiense infection in nine patients who are HIV-negative in Guangxi, China. International journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases. 2023; Vol 1 Num 128; 321–4 [cited 13 Ene 2025]; DOI:10.1016/j.ijid.2023.01.002. Disponible en: https://pubmed.ncbi.nlm.nih.gov/36642210/
[4] Rodrigues A, et al. A fatal case of pulmonary infection by Mycobacterium colombiense in Para State, Amazon Region, Brazil. Diagn Microbiol Infect Dis. 2016. Vol. 85 Num. 3, 344-6. [cited 13 Ene 2025]. DOI: 10.1016/j.diagmicrobio.2016.02.011. Disponible en: https://pubmed.ncbi.nlm.nih.gov/27133309/
[5] Pennington K, et al. Aproximación al diagnóstico y tratamiento de la enfermedad micobacteriana no tuberculosa. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases. 2021. Vol. 24 [citado 19 feb 2025]; DOI: https://doi.org/10.1016/j.jctube.2021.100244. Disponible en: https://www.sciencedirect.com/science/article/pii/S2405579421000334?via%3Dihub